Erythromycin ophthalmic preparations are used to treat infections of the eye. They also may be used to prevent certain eye infections of newborn babies, such as neonatal conjunctivitis and ophthalmia neonatorum. They may be used with other medicines for some eye infections. How to use Erythromycin Ointment. To apply eye ointment, wash your hands first. To avoid contamination, be careful not to touch the tip of the tube or let it touch your eye, eyelid, or any other. Erythromycin Ophthalmic Ointment Drug Information / Drug Summary email print Close window. Email this page. Send the page to a friend, relative, colleague or yourself. Your Name. Recipient's Email. Separate multiple email address with a comma. Erythromycin Ophthalmic Ointment belongs to the macrolide group of antibiotics. It is basic and readily forms a salt when combined with an acid. fect of erythromycin andqrisk of adverse GI reactions.qlevels and riskoftoxicity from alfentanil , alprazolam , bromocriptine , carbamazepine , cyclosporine , cilostazol diazepam disopyramide , ergot alkaloids , felodipine , methyl- Ophthalmic ointment Pull the lower eyelid down gently and squeeze a one-half–inch ribbon of the ointment into the sac, avoid touching the eye or lid. A mirror may be helpful. Prophylaxis for neonatal eye infection: Ribbon of ointment approximately 0.5–1 cm long is placed into lower conjunctival sac of neonate shortly after birth. Use a new tube of erythromycin for each neonate. Erythromycin Ophthalmic Ointment (Ilotycin) nursing considerations cleanse the infant's eyes as needed before application. Hold the tube in a horizontal rather than a vertical position to prevent injury to the eye from sudden movement. ILOTYCIN (erythromycin) Ointment. DESCRIPTION. ILOTYCIN™ Erythromycin Ophthalmic Ointment belongs to the macrolide group of antibiotics. It is basic and readily forms a salt when combined with an acid.